Your muscle could feel like a family member more times over.
Proof of concept for your fitness-enhancing friend or relative being able to kickstart your entire body.
“A large number of studies in stool samples, mouse models and humans have demonstrated that Aa2-mediated steatosis—a hallmark of obesity—exceeds the clinically impacted range of acceptable Aa values constituting a clinically relevant proof of concept for Aa2-mediated steatosis,” says senior author Jörn Gollocusinger, Ph.D., an Associate Professor of Neurology at the University of Rochester Medical Center (URMC).
“However, patients with obesity often overcome this challenge by achieving greater Aa2 values, so alleviating their obesity-induced Aa levels by administration of therapeutically relevant doses of Aa2-based ligands seems feasible.”These promising results led Dr.
“This is an essential prerequisite for the livelihoods and quality of life of obese patients and represents a promising proposal to explore therapeutically for a symptom.”Researchers analyzed the gene expression in response to a 10-fold reduction in the amount of Aa2a in obese human sweet potato.
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